 
					Transformative Computational Biology
SPARC partnered with the Biswas Family Foundation to advance the use of computational approaches in translational research and clinical settings through the Transformative Computational Biology Grant Program.
 
			Medical research propels global health and well-being. But, too often, innovation gets stuck—trapped by siloed fields, risk aversion, limited funding, and competing priorities—making it difficult to achieve the breakthroughs needed to improve human health.
SPARC brings together funders and stakeholders across disciplines and sectors to build strategic partnerships and programs that strengthen the biomedical ecosystem. We work with philanthropic organizations to invest in high-impact tools and approaches—such as artificial intelligence (AI), health equity, venture philanthropy, prevention-focused initiatives, and therapeutic development—that accelerate scientific progress.
By channeling philanthropic capital into cross-cutting areas of science, SPARC helps expand the infrastructure, talent, and resources necessary for systems-level change. Our efforts have contributed to transformative health discoveries and a more resilient, connected research ecosystem.
 
			 
					SPARC partnered with the Biswas Family Foundation to advance the use of computational approaches in translational research and clinical settings through the Transformative Computational Biology Grant Program.
 
						Health equity ensures everyone has a fair chance at good health, yet systemic barriers in research leave many communities behind. Philanthropy can help close these gaps by investing in inclusive research, community engagement, and workforce diversity.
 
						SPARC conducted a landscape analysis of health equity in science to identify where philanthropy can drive meaningful change. The Giving Smarter Guide outlines key trends, barriers, and opportunities to advance more equitable research and health outcomes.
 
						A new SPARC report, commissioned by The 10,000 Brains Project, highlights how AI and precision medicine can transform neurodegenerative disease research.