Science Ecosystem

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Medical research propels global health and well-being. But, too often, innovation gets stuck—trapped by siloed fields, risk aversion, limited funding, and competing priorities—making it difficult to achieve the breakthroughs needed to improve human health.

SPARC brings together funders and stakeholders across disciplines and sectors to build strategic partnerships and programs that strengthen the biomedical ecosystem. We work with philanthropic organizations to invest in high-impact tools and approaches—such as artificial intelligence (AI), health equity, venture philanthropy, prevention-focused initiatives, and therapeutic development—that accelerate scientific progress.

By channeling philanthropic capital into cross-cutting areas of science, SPARC helps expand the infrastructure, talent, and resources necessary for systems-level change. Our efforts have contributed to transformative health discoveries and a more resilient, connected research ecosystem.

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Active Funding Programs

Transformative Computational Biology

SPARC partnered with the Biswas Family Foundation to advance the use of computational approaches in translational research and clinical settings through the Transformative Computational Biology Grant Program.

Programmatic Areas

AI in Health

AI holds transformative potential to deepen our understanding of disease, accelerate translational research, and improve clinical care. SPARC has worked with several philanthropic partners to launch initiatives at the intersection of AI and health—advancing innovations that support the well-being of communities around the world.

Health Equity

Achieving health equity requires ensuring that everyone has a fair and just opportunity to attain their highest level of health. SPARC works to identify strategic pathways for philanthropy to help build community-centered research systems that drive more equitable health outcomes.

New Therapies and Prevention

Bringing new therapies and prevention tools to patients is a complex process, often slowed by high costs and lengthy timelines. SPARC works across the scientific ecosystem to identify strategic opportunities where philanthropy can accelerate progress in therapeutic development and disease prevention.

Cross-Disciplinary Programs

The complex health challenges facing us today demand bold innovation and collaboration across disciplines. SPARC advances interdisciplinary research by developing strategies that connect diverse areas of expertise, data, tools, and perspectives across sectors to work toward a shared goal.

Infrastructure and Resources for Systems Change

Coordinated, intentional philanthropy is essential not only for driving medical breakthroughs but also for building resilient biomedical systems capable of withstanding crises. SPARC develops strategic approaches to help funders invest more effectively in the infrastructure, resources, and workforce needed to catalyze systems-level change.

Organizational Strategy

Philanthropy is a critical tool for improving human health, but developing cohesive organizational strategies within the complex biomedical ecosystem can be challenging for nonprofit entities. SPARC partners with private funders, foundations, and nonprofits to craft strategic, mission-driven plans that maximize impact and drive meaningful progress.

Program Experts

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Cara Altimus, PhD

Managing Director

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Ishita Das, PhD

Director

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Taylor Evans, PhD

Senior Associate

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Cody Fisher, PhD

Senior Associate

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Kara Whelply, MBA, MPH

Associate Director

Related Content

Giving Smarter Guide
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Health Equity in Science: A Giving Smarter Guide 

SPARC conducted a landscape analysis of health equity in science to identify where philanthropy can drive meaningful change. The Giving Smarter Guide outlines key trends, barriers, and opportunities to advance more equitable research and health outcomes.