2025
												Frontotemporal dementia (FTD)
						 
					
										Uncovering the TDP-43 aggregate proteome and its role in FTLD pathogenesis
This research project seeks to determine and compare the molecular composition of diverse TDP-43 aggregates in FTLD-TDP brain tissue by using an innovative microscopy-guided proteomics approach and investigate the contribution of the identified TDP-43-associated proteins to the disease process in advanced tissue culture models of FTLD-TDP. Principal Investigator Wilfried Rossoll, PhD Mayo Clinic
